THE AKORN PROMETHAZINE CODEINE DIARIES

, ritonavir) or discontinuation of the cytochrome P450 3A4 inducer including rifampin, carbamazepine, and phenytoin, may lead to an increase in codeine plasma concentrations with subsequently increased metabolism by cytochrome P450 2D6, causing larger morphine stages, which could raise or extend adverse reactions and could trigger potentially letha